Daphne Hsu MD

Division Chief, Pediatric Cardiology Co-Director, Pediatric Heart Center Children's Hospital at Montefiore (CHAM) Professor of Pediatrics Albert Einstein College of Medicine Medical School: Yale University School of Medicine Residency: Pediatrics, Babies Hospital, Columbia Presbyterian Medical Center Fellowship: Pediatric Cardiology, Babies Hospital, Columbia Presbyterian Medical Center

Your child's pediatric cardiologist, Dr. Daphne Hsu, is one of the nation's leading experts in children's heart failure and heart transplant. Dr. Hsu has treated more than 600 children with heart failure and more than 250 children undergoing heart transplant. Past director of Pediatric Heart Failure at New York-Presbyterian Hospital, Dr. Hsu brings unique specialized medical skills, decades of experience-and extraordinary commitment-to the care of your child with complex heart disease.

When your child is being considered for a heart transplant, Dr. Hsu provides expert evaluation. Before, during and after surgery, she manages the full-spectrum, customized medical therapy-and hands-on specialized care-your child needs for successful heart transplant.

In addition to managing her busy practice, Dr. Hsu conducts ongoing clinical research and is a nationally recognized pediatric cardiologic thought-leader.

Since beginning her career in 1987, Dr. Hsu has participated in many important US multi-center studies on children's cardiomyopathies, medical and catheter-based therapy for heart disease in children and heart transplant. Dr. Hsu served on the end-point and steering committee of the only multi-centered, placebo-controlled trial studying the effect of Carvedilol in pediatric heart failure patients.

Past president and board member of the Pediatric Heart Transplant Study Group, Dr. Hsu also sits on the boards of the Pediatric Cardiomyopathy Registry and the Adult Congenital Heart Disease Committee for the American Heart Association. In addition to authoring dozens of peer-reviewed cardiologic studies (link: p. 41), Dr. Hsu reviews pediatric cardiologic-related grants for the Food and Drug Administration and the National Institutes of Health and is a member of the Sub Board of Pediatric Cardiology of the American Board of Pediatrics

Dr. Hsu was drawn to pediatric cardiology early in her career. "I like being able to care for the sickest children," she explains. Children with heart failure "have a terrible disease," says Dr. Hsu. "You have to figure out what it is. You have to treat it quickly. And you have to do it well-and then you can follow them for the rest of their lives."

Lasting relationships with her patients-and their families-are for Dr. Hsu among the most rewarding aspects her work. "You can share with the family the joy of this child who is doing so beautifully because you know where they've come from."  

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Selected publications

1. Addonizio LJ, Hsu DT, Fuzesi L, Smith CR, Rose EA.  Optimal timing of pediatric heart transplantation.  Circulation, 1989, 80(5):III-84-III-89.
2. Addonizio LJ, Hsu DT, Smith CR, Rose EA. Late complications in pediatric cardiac transplant recipients.  Circulation, 1990, 82(5):IV-295-301.
3. Hsu DT, Addonizio LJ, Hordof AJ, Gersony WM.  Morbidity of acute pulmonary embolus in pediatric patients evaluated for cardiac transplantation. J Am Coll Cardiol, 1991, 17:1621-1625.
4. Hsu DT, Weng ZC, Nicolosi AC, Detwiler PM, Sciacca R, Spotnitz HM. Quantitative effects of myocardial edema on the left ventricular pressure-volume relation in the isolated stored pig heart. J Thorac Cardiovasc Surg, 1993, 106(4):651-657.
5. Hsu DT, Garofano RP, Douglas JM, Michler RE, Quaegebeur JM, Gersony WM, Addonizio LJ. Exercise performance after pediatric heart transplantation. Circulation, 1993, 88(5pt2):II 238-242.
6. Addonizio LJ, Hsu DT, Douglas JM, Kichuk MR, Michler RE, Quaegebeur JM, Smith CR, Rose EA. Decreasing incidence of coronary disease in pediatric cardiac transplant recipients using increased immunosuppression. Circulation, 1993, 88(5pt2):II 224-239.
7. Michler RE, Edwards NM, Hsu D, Bernstein D, Fricker FJ, Miller J, Copeland J, Kaye MP, Addonizio L. Pediatric retransplantation. J Heart Lung Transplant, 1993, 12:S319-S327.
8. Kerstein D, Levy PS, Hsu DT, Hordof AJ, Gersony WM, Barst RJ. Blade balloon atrial septostomy in patients with severe primary pulmonary hypertension. Circulation, 1995, 91(7):2028-2035.
9. Hsu DT, Quaegebeur JM, Michler RE, Smith CR, Rose EA, Kichuk MR, Gersony WM, Douglas JF, Addonizio LJ.  Heart transplantation in children with congenital heart disease. J Am Coll Card, 1995, 26:743-749.
10. Zangwill S, Hsu D, Kichuk M, Stolar C, Haddad J, Stylianos S, Michler R, Addonizio L: The incidence and outcome of primary Epstein-Barr virus infection and lymphoproliferative disease in pediatric heart transplant recipients. J Heart Lung Transplant, 1998, 17:1161-1166.
11. Lamour JM, Addonizio LJ, Galantowicz ME, Quaegebeur JM, Mancini DM, Kichuk MR, Beniaminovitz A, Michler RE, Weinberg A, Hsu DT. Outcome after orthotopic cardiac transplantation in adults with congenital heart disease. Circulation, 1999, 100(19 Suppl):II200-205.
12. Weller RJ, Weintraub R, Addonizio LJ, Kichuk-Chrisant MR, Gersony WM, Hsu DT. Outcome of idiopathic restrictive cardiomyopathy in children. Am J Cardiol, 2002, 90(5):501-506.
13. Mital S, Addonizio LJ, Lamour JM, Hsu DT. Outcome of children with end-stage congenital heart disease waiting for cardiac transplantation. J Heart Lung Transplant, 2003, 22:147-153.
14. Pass, RH, Hijazi, A, Hsu, DT, Lewis, V, Hellenbrand, WE. Multicenter USA Amplatzer patent ductus arteriosus occlusion device trial: initial and one-year results. J Am Coll Cardiol. 2004, 44:513-519.
15. Jayakumar KA, Addonizio LJ, Kichuk-Chrisant MR, Galantowicz ME, Lamour JM, Quaegebeur JM, Hsu DT. Cardiac transplantation after the Fontan or Glenn procedure. J Am Coll Cardiol. 2004;44(10):2065-72.
16. Hsu DT. Biological and Psychological Differences in the Child and Adolescent Transplant Recipient. Pediatr Transplantation 2005:9:416-421.
17. Hsu DT, Naftel DC, Webber SA, Morrow WR, Canter CE, Chinnock RE, Clark ML, Kirklin JK. Lessons learned from the Pediatric Heart Transplant Study. Congenital Heart Disease. 2005 1(3):54-62.
18. Bernstein D, Naftel D, Chin C, Addonizio LJ, Gamberg P, Blume ED, Hsu D, Canter CE, Kirklin JK, Morrow WR; Pediatric Heart Transplant Study. Outcome of listing for cardiac transplantation for failed Fontan: a multi-institutional study. Circulation. 2006 Jul 25;114(4):273-80.
19. Towbin JA, Lowe AM, Colan SD, Sleeper LA, Orav EJ, Clunie S, Messere J, Cox GF, Lurie PR, Hsu D, Canter C, Wilkinson JD, Lipshultz SE. Incidence, causes, and outcomes of dilated cardiomyopathy in children. JAMA. 2006;296(15):1867-1876.
20. Canter C, Shaddy RE, Bernstein D, Hsu DT, Chrisant MRK, Kirklin JK, Kanter KR Higgins RSD, Blume ED, Rosenthal DN, Boucek MM, Uzark KC, Friedman AH, Young JK. Indications for Heart Transplantation in Pediatric Heart Disease. Circulation. 2007, 115(5):658-76.
21. Shaddy RE, Boucek MM, Hsu DT, Boucek RJ, Canter CE, Mahony L, Ross RD, Pahl E, Blume ED, Dodd DA, Rosenthal DN, Burr J, La Salle B, Lukas MA, Tani LY. Multicenter, randomized, placebo-controlled, double-blind trial of carvedilol in children with heart failure. JAMA. 2007, 298(10):1171-1179.